1 Result for "

PI3K-001

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PI3K-001" in MCE Product Catalog:

Cat. No.: HY-181741
Target:  

Cathepsin

Research Areas:  

Inflammation/Immunology

PI3K-001 is a cathepsin B-responsive prodrug and antifibrotic agent. PI3K-001 undergoes cathepsin B-mediated cleavage of the Val-Ala linker in fibrotic lung lesions to release an active PI3K inhibitor payload, while it remains stable in healthy tissues. PI3K-001 improves collagen deposition, tissue collapse and alveolar injury in fibrotic lung tissues. PI3K-001 is applicable for the research of pulmonary fibrosis .
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