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PK-11007

" in MedChemExpress (MCE) Product Catalog:
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Cat. No.: HY-128784
CAS No.: 874146-69-7
Purity:  98.73%
Research Areas:  

Cancer

PK11007 is a mild thiol alkylator with anticancer activity. PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels .
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