2 Results for "

PONV

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PONV" in MCE Product Catalog:

Cat. No.: HY-14405A
CAS No.: 414910-30-8
Purity:  99.08%
Synonyms: GW679769B
Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) .
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Cat. No.: HY-14405
CAS No.: 414910-27-3
Synonyms: GW679769
Research Areas:  

Neurological Disease

Casopitant (GW679769) is a potent, selective, brain-penetrant and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant antagonizes the emetic effects of Substance P (HY-P0201). Casopitant is also a substrate and weak to moderate inhibitor of CYP3A4. Casopitant is indicated for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) .
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