1 Result for "

PROTAC BCL6/IKZF1/3 Degrader-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PROTAC BCL6/IKZF1/3 Degrader-1" in MCE Product Catalog:

Cat. No.: HY-179075
Research Areas:  

Cancer

PROTAC BCL6/IKZF1/3 Degrader-1 is an orally active bifunctional PROTAC‑IMiD protein degrader that targets and degrades BCL6, IKZF1 and IKZF3. PROTAC BCL6/IKZF1/3 Degrader-1 induces ubiquitination and proteasome-mediated degradation of target proteins by recruiting E3 ubiquitin ligase, and triggers cell cycle arrest and apoptosis. PROTAC BCL6/IKZF1/3 Degrader-1 exhibits favorable anti-tumor activity in diffuse large B-cell lymphoma xenograft models. PROTAC BCL6/IKZF1/3 Degrader-1 can be used for the research of diffuse large B-cell lymphoma .
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