4 Results for "

PSD95-nNOS

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "PSD95-nNOS" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-100457
CAS No.: 866927-10-8
Purity:  97.24%
Target:  

iGluR

Research Areas:  

Neurological Disease

IC87201, an inhibitor of PSD95-nNOS protein-protein interactions, suppresses NMDAR-dependent NO and cGMP formation.
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Cat. No.: HY-175824
PSD-95/nNOS PPI-IN-1 is a inhibitor targeting the PSD-95/nNOS interaction with potential blood-brain barrier penetration. PSD-95/nNOS PPI-IN-1 binds to the PSD-95 PDZ2 domain with high affinity (Ki = 19.45 μM). PSD-95/nNOS PPI-IN-1 inhibits glutamate-induced excitotoxicity by reducing intracellular ROS levels and inhibiting apoptosis. PSD-95/nNOS PPI-IN-1 significantly reduces cerebral infarct volume in rat tMCAO models. PSD-95/nNOS PPI-IN-1 can be used for the study of acute ischemic stroke .
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Cat. No.: HY-155355
Target:  

iGluR

Research Areas:  

Neurological Disease

LY836 is an orally active neuroprotective agent. LY836 significantly blocks PSD95-nNOS association in cortical neurons. LY836 can be used in study ischemic stroke .
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Cat. No.: HY-100457R
CAS No.: 866927-10-8
Research Areas:  

Neurological Disease

IC87201 (Standard) is the analytical standard of IC87201 (HY-100457). This product is intended for research and analytical applications. IC87201, an inhibitor of PSD95-nNOS protein-protein interactions, suppresses NMDAR-dependent NO and cGMP formation.
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