2 Results for "

PX102

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PX102" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100443A
CAS No.: 1268244-85-4
Purity:  99.24%
Synonyms: trans-PX-102
Target:  

FXR Autophagy

Research Areas:  

Metabolic Disease

PX20606 trans racemate (PX-102 trans racemate) is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively .
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Cat. No.: HY-100443
CAS No.: 1268245-19-7
Synonyms: PX-102
Target:  

FXR

Research Areas:  

Cancer

PX20606 is an orally active agonist for farnesoid X receptor (FXR), with EC50 220 nM (mFXR) and 50 nM (hFXR), measured by Gal4-FXR assay. PX20606 induces the expression of tumor suppressor gene NDRG2, inhibits the tumor growth and metastasis in mouse HCC model. PX20606 exhibits hepatoprotective efficacy .
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