1 Result for "

PbTx3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PbTx3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-12545
CAS No.: 85079-48-7
Synonyms: PbTx-3
Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na + channel activator and has multiple active centers (A-ring lactone, C-42 of R side chain) . Brevetoxin-3 (PbTx-3) has a high affinity to site 5 of the voltage-sensitive Na + channels, inhibits the inactivation of Na + channels and prolongs the mean open time of these channels. Brevetoxin-3 (PbTx-3) repeated exposures can lead to prolonged airway hyperresponsiveness (AHR) and lung inflammation .
loading...
    loading...