4 Results for "

RAW 264.7 cell line

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "RAW 264.7 cell line" in MCE Product Catalog:

Cat. No.: HY-162425
Target:  

PGE synthase COX

Research Areas:  

Inflammation/Immunology Cancer

Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. Anti-inflammatory agent 78 has significant potency on PGE2, PGE1, COX-2 and COX-1 inhibition. Anti-inflammatory agent 78 can inhibits NO release in LPS-stimulated RAW 264.7 cell line .
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Cat. No.: HY-N2939
CAS No.: 870480-56-1
Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM .
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Cat. No.: HY-105825
CAS No.: 57645-05-3
Synonyms: SH-G 318AB
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Sermetacin (SH-G 318AB) is an anti-inflammatory agent with biocompatibility and anti-inflammatory activity. Sermetacin is stable in saline and suitable for compound delivery. Sermetacin exhibits good biocompatibility in the RAW 264.7 mouse macrophage cell line. The anti-inflammatory response of sermetacin is comparable to that of its parent compound, indomethacin. Sermetacin may show potential in future applications of self-delivery of compound delivery .
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Cat. No.: HY-159564
Target:  

COX NO Synthase

Research Areas:  

Inflammation/Immunology

iNOS/COX-2-IN-3 (compound 7d) is a dual inhibitor of iNOS and COX-2, with potential anti-inflammatory activity against LPS (HY-D1056)-induced RAW 264.7 cells (IC50=3.48 μM). iNOS/COX-2-IN-3 has good plasma stability, oral activity and gastric safety, and its inhibitory activity on iNOS and COX-2 expression is 5.43-fold and 2.37-fold that of Indomethacin (HY-14397), respectively .
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