iNOS/COX-2-IN-3
iNOS/COX-2-IN-3 (compound 7d) is a dual inhibitor of iNOS and COX-2, with potential anti-inflammatory activity against LPS (HY-D1056)-induced RAW 264.7 cells (IC50=3.48 μM). iNOS/COX-2-IN-3 has good plasma stability, oral activity and gastric safety, and its inhibitory activity on iNOS and COX-2 expression is 5.43-fold and 2.37-fold that of Indomethacin (HY-14397), respectively.
For research use only. We do not sell to patients.
- Formula: C46H64Cl2F2N6O16
- Molecular Weight:1065.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 1065.93
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Formula C46H64Cl2F2N6O16
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SMILES
O=C(C1=NN(C2=CC=C(F)C=C2)C(CCl)=N1)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC(C3=NN(C4=CC=C(F)C=C4)C(CCl)=N3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
iNOS/COX-2-IN-3 Related Classifications
HY-159564 Related Classifications
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