1 Result for "

RC33

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RC33" in MCE Product Catalog:

Cat. No.: HY-130179
CAS No.: 1346016-43-0
Target:  

Apoptosis

Research Areas:  

Neurological Disease

RC-33 hydrochloride is a selective and metabolically stable σ receptor agonist with activity in enhancing nerve growth factor (NGF)-induced neurite outgrowth. Both enantiomers of RC-33 hydrochloride bind to the σ receptor with similar affinity and show almost equal effectiveness as σ receptor agonists. The R-configured enantiomer of RC-33 hydrochloride shows higher liver metabolic stability in the presence of NADPH. RC-33 hydrochloride was selected as the best candidate for further in vivo studies in animal models of amyotrophic lateral sclerosis .
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