3 Results for "

RRMM

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "RRMM" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99730
CAS No.: 2227490-52-8
Synonyms: TAK-079

Target:  

CD38 Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) .
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Cat. No.: HY-P9989
CAS No.: 2408319-25-3
Synonyms: REGN5458

Target:  

CD3 TNF Receptor

Research Areas:  

Cancer

Linvoseltamab (REGN5458) is a bispecific T-cell engager (BiTE) antibody that specifically binds to B cell maturation antigen (BCMA) and CD3 of T cells, thereby directing T cells to multiple myeloma (MM) cells expressing BCMA and activating T cells to kill tumor cells. Linvoseltamab can be used in research of relapsed/refractory multiple myeloma (RRMM) .
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Cat. No.: HY-171754
Research Areas:  

Cancer

LM-305 is an anti-G protein-coupled receptor class 5 member D (GPRC5D) antibody-drug conjugate (ADC). LM-305 consists of Anti-GPRC5D Antibody (HY-P991197) and VcMMAE (HY-15575). LM-305 exhibits potent cytotoxicity against multiple myeloma cells (NCI-H929 and MM.1R) with IC50 values ranging from 0.1 to 0.3 nM. LM-305 can be used in the study of GPRC5D-related relapsed and refractory multiple myeloma (RRMM) .
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