2 Results for "

RXP470.1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "RXP470.1" in MCE Product Catalog:

Art. -Nr.: HY-135517
CAS. Nr.: 891198-31-5
Reinheit:  99.60%
Synonyms: RXP-470
Target:  

MMP

Forschungsgebiete:  

Cardiovascular Disease

RXP470.1 (RXP-470) is a potent, selective MMP-12 inhibitor with a Ki of 0.2 nM against human MMP-12. RXP470.1 is 2 to 4 orders of magnitude less potent against other MMPs. RXP470.1 significantly reduces atherosclerotic plaque cross-sectional area in mouse. RXP470.1 results in less complex plaques with increased smooth muscle cell:macrophage ratio, less macrophage apoptosis, increased cap thickness, smaller necrotic cores, and decreased incidence of calcification .
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Art. -Nr.: HY-135517A
Reinheit:  98.70%
Synonyms: (2R)-RXP-470
Target:  

MMP

Forschungsgebiete:  

Cardiovascular Disease

(2R)-RXP470.1 ((2R)-RXP-470) is the (2R)-isomer of RXP470.1 (HY-135517). RXP470.1 (RXP-470) is a potent, selective MMP-12 inhibitor with a Ki of 0.2 nM against human MMP-12 .
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