1 Result for "

Resigratinib

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Resigratinib" in MCE Product Catalog:

Cat. No.: HY-156632
CAS No.: 2750709-91-0
Purity:  99.53%
Synonyms: KIN-3248
Target:  

FGFR

Research Areas:  

Cancer

Resigratinib (KIN-3248) is an irreversible and orally active covalent inhibitor of FGFR1-4 that effectively inhibits wild-type and drug-resistant mutations (such as FGFR2 V565F, FGFR3 V555M). Resigratinib covalently binds to the Cys492 site of FGFR, blocks the FGFR signaling pathway, inhibits tumor cell proliferation and induces apoptosis. Resigratinib can be used for the study of FGFR2/3-driven solid tumors (such as cholangiocarcinoma and bladder cancer) .
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