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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
S2 subsites
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "S2 subsites" in MCE Product Catalog:
Cat. No.: HY-125494
CAS No.: 155662-50-3
Synonyms: SC-55389A
Target:
Research Areas:
Droxinavir hydrochloride (SC-55389A) is an HIV-1 protease inhibitor. Droxinavir hydrochloride binds to the S2 and S2' subsites of HIV-1 protease, and this interaction is regulated by protease amino acid residue 88, where the N88S mutation confers viral resistance. Droxinavir hydrochloride can be used in studies related to human immunodeficiency virus type 1 infection .
Cat. No.: HY-125494A
CAS No.: 159910-86-8
Synonyms: SC-55389A free base
Target:
Research Areas:
Droxinavir (SC-55389A free base) is an HIV-1 protease inhibitor. Droxinavir binds to the S2 and S2' subsites of HIV-1 protease, and this interaction is regulated by protease amino acid residue 88, where the N88S mutation confers viral resistance. Droxinavir can be used in studies related to human immunodeficiency virus type 1 infection .
Cat. No.: HY-189418
CAS No.: 2778223-60-0
Target:
Research Areas:
HL-3-68 is a SARS-CoV-2 main protease (MPro) inhibitor (IC50 = 0.29 μM; Ki = 0.89 μM; Kd = 0.75 μM). HL-3-68 stabilizes the primary binding site of MPro, locks the S1 and S2 subsites, and reduces loop flexibility. HL-3-68 is used for COVID-19 research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
