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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
SA-VA
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "SA-VA" in MCE Product Catalog:
Cat. No.: HY-155685
CAS No.: 3058085-77-8
Target:
Research Areas:
SA-VA is a heterobifunctional PROTAC molecule generated in situ via click chemistry, and acts as a degrader for VEGFR-2 and EphB4. SA-VA is self-assembled from the alkynyl precursor SA and the azide precursor VA through a copper ion-mediated intracellular click chemistry reaction, recruits the E3 ubiquitin ligase VHL to mediate the ubiquitination of target proteins, and triggers degradation via the proteasome pathway. SA-VA induces cell cycle arrest and apoptosis in U87 glioma cells. SA-VA can be used in cancer-related research .
Cat. No.: HY-RS14287
Target:
Research Areas:
TBXT Human Pre-designed siRNA Set A contains three designed siRNAs for TBXT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
