1 Result for "

SAS-0132

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SAS-0132" in MCE Product Catalog:

Cat. No.: HY-119386
CAS No.: 1644629-60-6
Research Areas:  

Neurological Disease

SAS-0132 is a selective Sigma 2 receptor (Sig2R) antagonist (Ki: 90 nM) that can cross the blood-brain barrier. SAS-0132 is capable of regulating intracellular Ca 2+ levels and modulating PGRMC1-related pathways. SAS-0132 exhibits neuroprotective activity and can improve cognitive impairment in Alzheimer's disease mice. SAS-0132 can be used in the research of neurocognitive disorders such as Alzheimer's disease .
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