1 Result for "

SC-919

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SC-919" in MCE Product Catalog:

Cat. No.: HY-171099
CAS No.: 2245949-62-4
Synonyms: LI-2124
Target:  

IPK Superfamily

SC-919 is an orally active IP6K inhibitor, with an IC50 of < 5.2 nM against IP6K1, < 3.8 nM against IP6K2, and 0.65 nM against IP6K3. By inhibiting the activity of IP6K, SC-919 reduces intracellular IP7 levels, thereby suppressing XPR1-mediated cellular phosphate efflux. SC-919 increases intracellular phosphate and ATP levels while reducing phosphate entry into the bloodstream, thus decreasing plasma phosphate levels. SC-919 can be used in research related to chronic kidney disease and hyperphosphatemia .
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