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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
SCA 136
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "SCA 136" in MCE Product Catalog:
5
Target:
Research Areas:
Vabicaserin hydrochloride (SCA-136) is a brain-penetrant, orally active, and selective 5-HT2C receptor agonist (Ki = 3 nM; EC50 = 8 nM). Vabicaserin hydrochloride specifically activates Gq-coupled 5-HT2C receptors to promote calcium mobilization, thereby selectively reducing dopamine release in the mesolimbic system without affecting the nigrostriatal pathway . Vabicaserin hydrochloride is an antagonist of 5-HT2A/5-HT2B receptors. Vabicaserin hydrochloride can be used for research on schizophrenia, obesity, chronic pain, and neurodegenerative diseases (such as Machado-Joseph disease) .
Cat. No.: HY-111200R
CAS No.: 887258-94-8
Synonyms: SCA 136 (Standard)
Target:
Vabicaserin hydrochloride (SCA 136) Standard is the analytical standard of Vabicaserin hydrochloride (HY-111200). This product is intended for research and analytical applications. Vabicaserin hydrochloride (SCA-136) is a brain-penetrant, orally active, and selective 5-HT2C receptor agonist (Ki = 3 nM; EC50 = 8 nM). Vabicaserin hydrochloride specifically activates Gq-coupled 5-HT2C receptors to promote calcium mobilization, thereby selectively reducing dopamine release in the mesolimbic system without affecting the nigrostriatal pathway . Vabicaserin hydrochloride is an antagonist of 5-HT2A/5-HT2B receptors. Vabicaserin hydrochloride can be used for research on schizophrenia, obesity, chronic pain, and neurodegenerative diseases (such as Machado-Joseph disease) .
Cat. No.: HY-111200A
CAS No.: 887258-95-9
Synonyms: SCA-136 free base
Target:
Research Areas:
Vabicaserin (SCA-136 free base) is a brain-penetrant, orally active, and selective 5-HT2C receptor agonist (Ki = 3 nM; EC50 = 8 nM). Vabicaserin specifically activates Gq-coupled 5-HT2C receptors to promote calcium mobilization, thereby selectively reducing dopamine release in the mesolimbic system without affecting the nigrostriatal pathway . Vabicaserin is an antagonist of 5-HT2A/5-HT2B receptors. Vabicaserin can be used for research on schizophrenia, obesity, chronic pain, and neurodegenerative diseases (such as Machado-Joseph disease) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
