1 Result for "

SHY855

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHY855" in MCE Product Catalog:

Cat. No.: HY-178194
CAS No.: 2446485-15-8
Target:  

Ras MEK ERK Akt

Research Areas:  

Cancer

SHY-855 is a pan RAS inhibitor. SHY-855 effectively prevents the binding of K-Ras proteins and other members of the Ras superfamily of small GTPases with IC50 values of 0.3-5 μM. SHY-855 effectively inhibits the phosphorylation of MEK, ERK1/2, and AKT downstream of K-Ras. SHY-855 inhibits the formation of the Ras-GTP activity complex. SHY-855 can be used to the studies of pancreatic cancer and non-small cell lung cancer .
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