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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
SMYD3 Inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "SMYD3 Inhibitor" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-19324
CAS No.: 2095161-11-6
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EPZ031686 is an potent and orally active SMYD3 inhibitor and with an IC50 value of 3 nM. EPZ031686 can be used for cancer research .
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5 Cited Publications
Cat. No.: HY-21972
CAS No.: 432529-82-3
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BCI-121 is a SMYD3 inhibitor that impairs the proliferation of cancer cell.
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EM127 (compound 11c) is a SMYD3 covalent inhibitor with high selectivity, high affinity (KD=13 μM) and site-specificity. EM127 effectively inhibits ERK1/2 phosphorylation and reduces transcriptional regulation of SMYD3 target genes. EM127 effectively and prolongedly impairs methyltransferase activity. EM127 can be used in cancer research, particularly in SMYD3 positive tumours .
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GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM .
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BAY-6035, a chemical probe, is a potent, selective and substrate-competitive inhibitor of SMYD3. BAY-6035 inhibits methylation of MEKK2 peptide with an IC50 of 88 nM .
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SMYD3-IN-1 (compound 29) is an irreversible and selective inhibitor of SMYD3 (SET and MYND domain containing 3), with an IC50 of 11.7 nM .
Cat. No.: HY-122223
CAS No.: 1808011-23-5
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EPZ030456 is a potent and selective SMYD3 inhibitor with an IC50 of 48 nM. EPZ030456 can be used for cancer research .
Cat. No.: HY-152228
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Cat. No.: HY-145444
CAS No.: 1887082-53-2
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EPZ028862 is a selective SMYD3 inhibitor for cancer research .
Cat. No.: HY-104009
CAS No.: 2245255-65-4
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GSK2807 is a potent and selective SAM-competitive inhibitor of SMYD3, exhibiting a Ki value of 14 nM, and it may be useful for cancer treatment by preventing the methylation of MEKK2.
Cat. No.: HY-112080A
CAS No.: 2283389-29-5
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(R)-BAY-6035 is a novel inhibitor that selectively targets the methylation of MAP3K2 by SMYD3, demonstrating nanomolar potency and specificity against kinases and other protein lysine methyltransferases.
Cat. No.: HY-104009AR
CAS No.: 2245255-66-5
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GSK2807 Trifluoroacetate (Standard) is the analytical standard of GSK2807 Trifluoroacetate (HY-104009A). This product is intended for research and analytical applications. GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive inhibitor of SMYD3, with a Ki of 14 nM and an IC50 of 130 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
