1. Epigenetics
  2. Histone Methyltransferase
  3. EPZ031686

EPZ031686 

Cat. No.: HY-19324 Purity: 99.63%
Handling Instructions

EPZ031686 is an orally available SMYD3 inhibitor with an IC50 of 3 nM in cell-free assay.

For research use only. We do not sell to patients.

EPZ031686 Chemical Structure

EPZ031686 Chemical Structure

CAS No. : 1808011-22-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 546 In-stock
Estimated Time of Arrival: December 31
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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  • Purity & Documentation

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Description

EPZ031686 is an orally available SMYD3 inhibitor with an IC50 of 3 nM in cell-free assay.

Molecular Weight

591.09

Formula

C₂₆H₃₄ClF₃N₄O₄S

CAS No.

1808011-22-4

SMILES

O=C(C1)NC2=C1C=C(C(N[[email protected]@H]3C[[email protected]]4N(S(CC5CCN(CCCC(F)(F)F)CC5)(=O)=O)[[email protected]](CC4)C3)=O)C(Cl)=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 5.9 mg/mL (9.98 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6918 mL 8.4589 mL 16.9179 mL
5 mM 0.3384 mL 1.6918 mL 3.3836 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  30% PEG300  70% (20% SBE-β-CD in saline)

    Solubility: 10 mg/mL (16.92 mM); Suspended solution; Need ultrasonic and warming

*All of the co-solvents are provided by MCE.
References

Purity: 99.63%

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Product Name:
EPZ031686
Cat. No.:
HY-19324
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