4 Results for "

SS28

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "SS28" in MCE Product Catalog:

Cat. No.: HY-106103
CAS No.: 81377-02-8
Pureté:  99.30%
Synonyms: MK-678; L-363586
Seglitide (MK-678) is an orally active, selective SSTR2 agonist and somatostatin analog. Seglitide also acts as a competitive Somatostatin receptor antagonist, with pA2 values of 6.50, 6.24 and 6.09 against SS14, SS25 and SS28, respectively. Seglitide produces only weak, transient inhibition of myocardial contractility in isolated right atria of guinea pigs. Seglitide inhibits glucagon secretion and reduces circulating insulin levels. Seglitide causes a sustained, reversible reduction in elevated systolic blood pressure in streptozotocin (HY-13753)-induced diabetic rats, but exerts no effect on spontaneously hypertensive rats. Seglitide induces membrane hyperpolarization and inhibits electrical excitability. Seglitide induces concentration-dependent contraction and significant desensitization in isolated distal colon of rats. Seglitide can be used in research related to hypertension complicated with insulin-dependent diabetes mellitus .
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Cat. No.: HY-100761
CAS No.: 141172-08-9
Domaines de recherche:  

Cancer

SS28, a SRT501 analog with oral bioavailability, inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase. SS28 results in apoptosis rather than necrosis tubulin .
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Cat. No.: HY-149861
CAS No.: 2984599-57-5
Target:  

Bacterial

Domaines de recherche:  

Infection

Mip-IN-1(S,S-28i)is a new rapamycin-derived macrophage infectivity potentiator (Mip) inhibitor. Mip-IN-1 displays strong anti-enzymatic activity against the Mip proteins of Neisseria meningitidis and Neisseria gonorrhoeae and substantially improved the ability of macrophages to kill the bacteria .
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Cat. No.: HY-RS24497
Domaines de recherche:  

Others

Sst Rat Pre-designed siRNA Set A contains three designed siRNAs for Sst gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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