1 Result for "

Se2h

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Se2h" in MCE Product Catalog:

Cat. No.: HY-159915
Target:  

Parasite

Domaines de recherche:  

Infection

Se2h is a cruzain inhibitor that exhibits strong activity against the intracellular amastigotes of Trypanosoma cruzi (EC50 < 1 μM, SI > 10), with an inhibitory activity against cruzain of IC50 < 100 nM (SI > 5.55). Compared to Benznidazole (HY-B1548) and the cruzain inhibitor K777 (HY-119293), Se2h shows superior selectivity and inhibition, while its selenazole structure reduces selenium-related toxicity. Se2h exhibits antiparasitic activity and holds promise for research in Chagas disease .
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