7 Results for "

T84

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "T84" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-B0679
CAS No.: 136790-76-6
Synonyms: RU-0211; SPI-0211
Lubiprostone (SPI-0211) increases intestinal fluid secretion through generation of CIC-2/CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research .
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Cat. No.: HY-108741
CAS No.: 467426-54-6
Purity:  99.93%
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology Cancer

Plecanatide, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide shows anti-inflammatory activity in models of murine colitis .
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Cat. No.: HY-N9445
CAS No.: 13007-32-4
Synonyms: LNnT
Lacto-N-neotetraose (LNnT) is an endogenous metabolite. Lacto-N-neotetraose can inhibit TNF-α induced IL-8 secretion in immature epithelial cells. Lacto-N-neotetraose has anti-inflammatory avtivity, and can improve the wound closure .
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Cat. No.: HY-108741A
CAS No.: 1075732-84-1
Purity:  99.51%
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology Cancer

Plecanatide acetate, an analogue of Uroguanylin, is an orally active guanylate cyclase-C (GC-C) receptor agonist. Plecanatide acetate activates GC-C receptors to stimulate cGMP synthesis with an EC50 of 190 nM in T84 cells assay. Plecanatide acetate can be used for the research of chronic idiopathic constipation, and it also shows anti-inflammatory activity in models of murine colitis .
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Cat. No.: HY-P3499
CAS No.: 1092457-65-2
Target:  

Guanylate Cyclase

Research Areas:  

Inflammation/Immunology

Dolcanatide is an orally active GC-C (guanylate cyclase-C) agonist. Dolcanatide shows laxative, anti-nociceptive and anti-inflammatory activity. Dolcanatide can be used in inflammatory bowel disease research .
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Cat. No.: HY-N12323
CAS No.: 32581-31-0
6′-Galactosyllactose is the main oligosaccharide that makes up galactose, a component of human milk. 6′-Galactosyllactose can synthesize human milk oligosaccharides and synthetic galactosyllactose with 3′-Galactosyllactose and 4′-Galactosyllactose, and reduce inflammation in human T84, NCM-460 and H4 cells and intestinal tissues .
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Cat. No.: HY-401913
CAS No.: 345288-49-5
Research Areas:  

Infection Cancer

Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .
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