1 Result for "

T863

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "T863" in MCE Product Catalog:

15
15 Cited Publications
Cat. No.: HY-32219
CAS No.: 701232-20-4
Target:  

Acyltransferase

Research Areas:  

Metabolic Disease

T863 is an orally active, selective and potent DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1) inhibitor with an IC50 of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells .
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