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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
TAP
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "TAP" in MCE Product Catalog:
YX-02-030 is a VHL-dependent MDM2 PROTAC degrader with a Kd of 35 nM. YX-02-030 recruits the VHL E3 ligase to form a ternary complex, leading to ubiquitination and proteasome-mediated degradation of MDM2. YX-02-030 inhibits MDM2-p53 and VHL-HIF1α binding with IC50 values of 63 and 1350 nM. YX-02-030 activates TAp73, upregulates p53 family target genes and induces apoptosis. YX-02-030 demonstrates on-target efficacy in TNBC xenograft-bearing mice, extending survival without normal cell toxicity .
Cat. No.: HY-P1192
CAS No.: 133156-06-6
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Cat. No.: HY-107997
CAS No.: 1149362-88-8
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TAP311 is a cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 62 nM .
Cat. No.: HY-129448
CAS No.: 825643-56-9
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RO4583298 is a potent, orally active dual antagonist of NK1 (human and gerbil)/NK3 (human, cynomolgus monkey, gerbil and guinea-pig). RO4583298 inhibits senktide-induced potentiation of spontaneous activity of dopaminergic neurons. RO4583298 can block gerbil foot tapping response and inhibits mouse tail whips .
Cat. No.: HY-P5865
Synonyms: Theraphotoxin-TAP1a; TRTX-TAP1a; µ/ω-TRTX-TAP1a
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Cat. No.: HY-157051
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[Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT) .
Cat. No.: HY-RS14201
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TAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14202
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TAP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TAP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18500
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Tap2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tap2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24053
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Tap1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tap1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24982
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Tap2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tap2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09710
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NXF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NXF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17593
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Tap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15519
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USO1 Human Pre-designed siRNA Set A contains three designed siRNAs for USO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156372
CAS No.: 2758685-58-2
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AChE-IN-44 (Compound Tap4) is an AChE inhibitor. AChE-IN-44 can be converted into the thiazole salt AChE inhibitor Tat2 .
Cat. No.: HY-RS12607
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SEC14L2 Human Pre-designed siRNA Set A contains three designed siRNAs for SEC14L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P4461
CAS No.: 99524-09-1
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Cat. No.: HY-RS04980
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FLNB Human Pre-designed siRNA Set A contains three designed siRNAs for FLNB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-172826
Anti-MRSA agent 26 is a potent anti-MRSA agent with MIC <0.015 μg/mL. Anti-MRSA agent 26 has superior activity against a broad range of Gram-positive pathogens and shows no cytotoxicity in three mammalian cell lines (Caco-2, DU-145 and MDCKII MDR1 cells) at 10 μM. Anti-MRSA agent 26 has a robust TAP pharmacophore and an excellent antibacterial activity in Staphylococcus aureus skin infection mice model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
