1 Result for "

TAS2R31

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TAS2R31" in MCE Product Catalog:

Cat. No.: HY-124956
CAS No.: 957136-80-0
Research Areas:  

Metabolic Disease

GIV3727 is an orally active bitter taste receptor antagonist targeting TAS2R4, TAS2R7, TAS2R20, TAS2R31, TAS2R40, and TAS2R43, with orthosteric, insurmountable antagonism at hTAS2R31. GIV3727 blocks TAS2R4 and prevents Gallic acid-induced upregulation of GDF15 mRNA expression. GIV3727 inhibits agonist-evoked receptor activation. GIV3727 reduces the perceived bitterness of acesulfame K and saccharin without affecting sweet taste perception. GIV3727 can be used for obesity research .
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