1 Result for "

TBA7371

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TBA7371" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-19750
CAS No.: 1494675-86-3
Target:  

Bacterial

Research Areas:  

Infection

TBA-7371 is an orally active and non-covalent inhibitor of Decaprenylphosphoryl-β-D-ribose oxidase (DprE1) of Mycobacterium tuberculosis (MIC=0.64 μg/mL). TBA-7371 can block the synthesis of arabinose in the bacterial cell wall, resulting in cell wall structural defects, thereby exerting an anti-tuberculosis effect. TBA-7371 can be used in the research of anti-tuberculosis drugs and has a synergistic bactericidal effect with Bedaquiline (HY-14881) and other drugs .
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