1 Result for "

TP004

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "TP004" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-120868
CAS No.: 1454299-21-8
Purity:  99.17%
Target:  

MetAP

Research Areas:  

Metabolic Disease Cancer

TP-004 is a potent and reversible inhibitor of methionine aminopeptidase 2 (MetAP2), with an IC50 of 6 nM against MetAP2. TP-004 is a chemical probe. TP-004 suppresses MetAP2 enzymatic activity, blocks N-terminal methionine cleavage, impairs protein maturation and stability, and thereby inhibits cell proliferation and angiogenesis. TP-004 can be used for the study of tumors and diseases associated with excessive angiogenesis .
loading...
    loading...