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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
TP2
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "TP2" in MCE Product Catalog:
Cat. No.: HY-157930
Target:
Research Areas:
TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs). TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible .
Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 μM, and has potent anti-tuberculosis activity .
Cat. No.: HY-RS14858
Target:
Research Areas:
TNP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TNP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81110A
Synonyms: Telomerase catalytic subunit; EST2; hEST2; TCS1; Telomerase associated protein 2; Telomere Reverse Transcriptase; TP2; TRT; Telomerase reverse transcriptase; Telomerase Catalytic Subunit; Telomerase-associated protein 2; TERT_HUMAN.
Cat. No.: HY-P704039
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Human
Source:
E. coli
Cat. No.: HY-RS14376
Target:
Research Areas:
Tert Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tert gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14375
Target:
Research Areas:
TERT Human Pre-designed siRNA Set A contains three designed siRNAs for TERT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81110
Synonyms: Telomerase catalytic subunit; EST2; hEST2; TCS1; Telomerase associated protein 2; Telomere Reverse Transcriptase; TP2; TRT; Telomerase reverse transcriptase; Telomerase Catalytic Subunit; Telomerase-associated protein 2; TERT_HUMAN.
Cat. No.: HY-173211
Target:
Research Areas:
anti-TNBC agent-8 (Compound TP2) is a photodynamic therapeutic agent targeting mitochondrial DNA G4 (mtG4). Under white light irradiation, its IC50 against 4T1 cells is 0.42 μM. anti-TNBC agent-8 binds tightly to mtG4 and generates a large amount of reactive oxygen species (ROS) under white light irradiation, leading to the loss of mitochondrial membrane potential (MMP), a decrease in ATP production, and an increase in the ROS level. This, in turn, induces significant apoptosis in triple-negative breast cancer (TNBC) cells, exerting the activity of inhibiting tumor cell growth. anti-TNBC agent-8 can be used in the research of triple-negative breast cancer.
Cat. No.: HY-176143
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
P2Y1/P2Y6 antagonist 1 (Compound 3h) is an indolesulfonylhydrazide derivative. P2Y1/P2Y6 antagonist 1 is an orally active tP2Y1 and rP2Y6 antagonist (IC50 of 9.72 and 1.89 μM, respectively). P2Y1/P2Y6 antagonist 1 can be used in the study of neurological diseases, inflammation, cardiovascular diseases and cancer .
Cat. No.: HY-P703520
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Others
Source:
E. coli
Cat. No.: HY-P703522
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Others
Source:
E. coli
Cat. No.: HY-P703521
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TERT; Telomerase Catalytic Subunit; Telomerase Reverse Transcriptase; Telomerase-Associated Protein 2; HEST2; PFBMFT1; TCS1; DKCA2; EST2; DKCB4; TRT; CMM9; TP2; HTRT
Species:
Others
Source:
E. coli
Cat. No.: HY-183716
CAS No.: 2489184-70-3
Target:
Research Areas:
Mito-TP-2 is a triptolide (HY-32735) derivative. Mito-TP-2 exhibits concentration-dependent cytotoxicity in cancer cells. Mito-TP-2 is selectively driven and accumulated into the mitochondria of tumor cells by mitochondrial transmembrane potential and exerts specific mitochondrial toxicity. Mito-TP-2 can be used for the research of liver cancer, breast cancer, and non-small cell lung cancer [2] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
