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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
TT012
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "TT012" in MCE Product Catalog:
2
2 Cited Publications
Research Areas:
TT-012 is a MITF inhibitor with a human MITF IC50 of 13.1 nM and a human MITF Kd value of 15.5 nM. TT-012 reduces mRNA levels of MITF downstream genes linked to melanosome biogenesis, cell survival, and proliferation, and upregulates cell cycle-inhibiting genes. TT-012 can be used for the research of melanoma[1][2][3].
Cat. No.: HY-179718
Research Areas:
TT-012-Br (Compound 4) is a ligand for MITF and can be used for the synthesis of PROTACs, such as WZS0347 (HY-179717) .
Cat. No.: HY-179720
Research Areas:
WZS0347 Ligand-Linker Conjugate 1 (Compound 5d) is a synthetic target protein ligand-linker conjugate, which can be used for the synthesis of PROTACs, such as WZS0347 (HY-179717). WZS0347 is a potent MITF PROTAC degrader with anti-cancer activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
