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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Tapinarof
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Tapinarof" in MCE Product Catalog:
15
15 Cited Publications
Synonyms: WBI-1001; Benvitimod; GSK2894512
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Research Areas:
Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice .
Cat. No.: HY-176771
CAS No.: 2901016-08-6
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Research Areas:
Tapinarof prodrug-1 (Compound 31) is an orally active prodrug of Tapinarof (HY-109044). Tapinarof is an AhR agonist. Tapinarof prodrug-1 has an improving effect in the TNBS-induced mouse model of inflammatory bowel disease. Tapinarof prodrug-1 can be used in the research of inflammatory diseases .
Cat. No.: HY-109044R
CAS No.: 79338-84-4
Synonyms: WBI-1001 (Standard); Benvitimod (Standard); GSK2894512 (Standard)
Research Areas:
Tapinarof (Standard) is the analytical standard of Tapinarof. This product is intended for research and analytical applications. Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice .
Cat. No.: HY-178053
CAS No.: 1191937-43-5
Research Areas:
AHR agonist 10 is a potent AHR agonist (EC50 = 2.01 nM). AHR agonist 10 can elevate the transcript levels of key AHR downstream pathway target genes, including CYP1A1 and CYP1B1. AHR agonist 10 can downregulate the expression levels of CD36, IL-18 and shows low cytotoxicity (>40 μM) to normal cells. AHR agonist 10 can suppress the expression of CCL5, CCL20, IL-6, IL-8, S100A9, TLR4, TNF-α, and TNFR1, demonstrating that AHR agonist 10 effectively modulate inflammatory responses through AHR dependent signaling pathways. AHR agonist 10 can be used for psoriasis research .
Cat. No.: HY-109044S
CAS No.: 2748997-80-8
Synonyms: WBI-1001-d5; Benvitimod-d5; GSK2894512-d5
Cat. No.: HY-59097
CAS No.: 115781-08-3
Synonyms: (E/Z)-WBI-1001; (E/Z)-Benvitimod; (E/Z)-GSK2894512
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
