1 Result for "

Topoisomerase I/II-IN-10

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Topoisomerase I/II-IN-10" in MCE Product Catalog:

Cat. No.: HY-189664
Research Areas:  

Cancer

Topoisomerase I/II-IN-10 is a Topoisomerase I/II inhibitor. Topoisomerase I/II-IN-10 inhibits TrxR1 activity, impairs the thioredoxin antioxidant system, and promotes oxidative stress. Topoisomerase I/II-IN-10 does not intercalate into DNA and does not induce DNA relaxation in the absence of topoisomerase. Topoisomerase I/II-IN-10 induces Apoptosis, increases the intracellular total oxidation state, and increases the Bax/Bcl-2 ratio. Topoisomerase I/II-IN-10 can be used for research on lung cancer .
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