1 Result for "

Topoisomerase II inhibitor23

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Topoisomerase II inhibitor23" in MCE Product Catalog:

Cat. No.: HY-174404
Research Areas:  

Cancer

Topoisomerase II inhibitor 23 is a potent topoisomerase II inhibitor (IC50 = 0.94 μM). Topoisomerase II inhibitor 23 shows high selectivity and exceptional cytotoxic activity in MCF-7, HepG2, and HCT116 cells. Topoisomerase II inhibitor 23 induces cell cycle arrest at the G1 phase, leading to inhibition of cell proliferation. Topoisomerase II inhibitor 2 induces apoptosis by up-regulating the pro-apoptotic Bax level and down-regulating the anti-apoptotic Bcl-2 level.
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