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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
U-118MG cells
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "U-118MG cells" in MCE Product Catalog:
Cat. No.: HY-178969
Research Areas:
GZD-257 is a brain-penetrant, ATP-competitive FAK inhibitor (IC50 = 14.3 nM), performing 4.77-fold selectivity with FAK to Pyk2 (IC50 = 68.2 nM). GZD-257 can significantly induce apoptosis of U118MG cells and arrest the cell cycle at the G2/M phase. GZD-257 can be used for the study of Glioblastoma (GBM) .
Cat. No.: HY-187711
Target:
Research Areas:
FAK-IN-33 is a potent focal adhesion kinase (FAK) inhibitor with an IC50 value of 10.23 nM against FAK. FAK-IN-33 inhibits the viability of U118-MG glioblastoma cells with an IC50 of 0.29 μM, and shows low cytotoxicity toward LO2 and 2BS cells. FAK-IN-33 can be used in studies related to glioblastoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
