1 Result for "

USP7-797

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "USP7-797" in MCE Product Catalog:

Cat. No.: HY-136910
CAS No.: 2413944-70-2
Purity:  99.09%
Synonyms: USP7-IN-7
Research Areas:  

Cancer

USP7-797 (USP7-IN-7) is an orally available, selective USP7 inhibitor (IC50=0.5 nmol/L) with antitumor activity. USP7-797 reduces the level of MDM2, thereby increasing the stability and activity of p53, leading to cell cycle arrest and apoptosis. USP7-797 has low nanomolar cytotoxicity against p53 mutant cancer cell lines, p53 wild-type hematological tumors, and neuroblastoma cell lines .
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