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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
84 Results for "
Ubiquitin conjugating enzyme
" in MedChemExpress (MCE) Product Catalog:
Products (84)
84 Results for "Ubiquitin conjugating enzyme" in MCE Product Catalog:
8
8 Publications Verification
Target:
Research Areas:
NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity .
4
4 Cited Publications
Cat. No.: HY-P79449
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2D2; Ubiquitin conjugating enzyme E2 D2; UBC4; UbcH5B; Ubiquitin‑conjugating enzyme E2D 2 (Homologous To Yeast UBC4/5); (E3‑Independent) E2 Ubiquitin‑conjugating enzyme D2; P53‑Regulated Ubiquitin‑conjugating enzyme 1; Ubiquitin‑conjugating enzyme E2‑1
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P70998
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2D3; Ubiquitin conjugating enzyme E2 D3; UbcH5C; Ubiquitin‑conjugating enzyme E2D 3 (Homologous To Yeast UBC4/5); Ubiquitin‑conjugating enzyme E2D 3 (UBC4/5 Homolog,Yeast); (E3‑Independent) E2 Ubiquitin‑conjugating enzyme D3; Ubiquitin‑conjugating Enzy
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P79451
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L3; Ubiquitin conjugating enzyme E2 L3; UBCH7; Ubiquitin‑conjugating enzyme E2 L3; E2 Ubiquitin‑conjugating enzyme L3; Ubiquitin‑conjugating enzyme E2‑F1; Ubiquitin Carrier Protein L3; Ubiquitin‑Protein Ligase L3; L‑UBC; Ubiquitin‑conjugating enzyme E
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P74484
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: UBE2B; Ubiquitin conjugating enzyme E2 B; HHR6B; RAD6B; UBC2; Ubiquitin‑conjugating enzyme E2B (RAD6 Homolog); Ubiquitin‑conjugating enzyme E2‑17 KDa; Ubiquitin‑conjugating enzyme E2 B; E2 Ubiquitin‑conjugating enzyme B; Ubiquitin Carrier Protein B; Ubiqu
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P71398
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2B; RAD6B; UBCH1; Ubiquitin-conjugating enzyme E2 B; EC 2.3.2.23; E2 Ubiquitin-conjugating enzyme B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B
Species:
Human
Source:
HEK293
Target:
Research Areas:
CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27 Kip1, as confirmed by dose-response analysis.
Target:
Research Areas:
UbcH5c-IN-1 (compound 6d) is a potent and selective small-molecule inhibitor of Ubiquitin-conjugating enzyme UbcH5c, with a Kd of 283 nM for E2 UbcH5c-IN-1 by covalent binding with Cys85. A promising lead compound for the development of new antirheumatoid arthritis (RA) agent .
Cat. No.: HY-E70618
Target:
Research Areas:
Ubiquitin Conjugating enzyme E2C (EC 2.3.2.24) is a member of the E2 ubiquitin-conjugating enzyme family, and it is the principal regulator of pathways for protein degradation in eukaryotes. Ubiquitin Conjugating enzyme E2C is involved in the tumorigenesis of various malignancies. Ubiquitin Conjugating enzyme E2C is also involved in mitotic cyclin disruption, affecting cell cycle progression. Ubiquitin Conjugating enzyme E2C is a prognostic indicator for cholangiocarcinoma .
Cat. No.: HY-E71082
Target:
Research Areas:
(E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) transfers a single ubiquitin directly from an ubiquitinated E1 ubiquitin-activating enzyme to itself, and on to a lysine residue of the acceptor protein without involvement of E3 ubiquitin transferases.
Cat. No.: HY-161960
Research Areas:
EP300/CBP ligand 2 (compound S19) is a ligand targeting the bromodomain of CREB binding protein (CBP) and E1A-associated protein (EP300). EP300/CBP ligand 2 can be used as a target protein ligand in the PROTAC structure, and can be coupled to the E3 ubiquitin ligase ligand through the PTOTAC Linker to synthesize PROTAC molecules with degradation effects. For example, EP300/CBP ligand 2 can be coupled with the conjugate (E3 ubiquitin enzyme ligand + Linker) Thalidomide-NH-C10-Boc (HY-161961) to produce the PROTAC molecule dCE-2 (HY-161958) .
Cat. No.: HY-P71402
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2H; Ubiquitin conjugating enzyme E2 H; (E3‑Independent) E2 Ubiquitin‑conjugating enzyme H; Ubiquitin‑conjugating enzyme E2‑20K; Ubiquitin‑conjugating enzyme E2 H; E2 Ubiquitin‑conjugating enzyme H; Ubiquitin Carrier Protein H; Ubiquitin‑Protein Ligase
Species:
Human
Source:
E. coli
Cat. No.: HY-P71408
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2S; Ubiquitin conjugating enzyme E2 S; E2‑EPF; Ubiquitin‑conjugating enzyme E2‑24 KDa; Ubiquitin‑conjugating enzyme E2‑EPF5; Ubiquitin‑conjugating enzyme E2 S; E2 Ubiquitin‑conjugating enzyme S; Ubiquitin Carrier Protein S; Ubiquitin‑Protein Ligase S;
Species:
Human
Source:
E. coli
Cat. No.: HY-P703297
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L3; Ubiquitin conjugating enzyme E2 L3; UBCH7; Ubiquitin‑conjugating enzyme E2 L3; E2 Ubiquitin‑conjugating enzyme L3; Ubiquitin‑conjugating enzyme E2‑F1; Ubiquitin Carrier Protein L3; Ubiquitin‑Protein Ligase L3; L‑UBC; Ubiquitin‑conjugating enzyme E
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P703298
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L3; Ubiquitin conjugating enzyme E2 L3; UBCH7; Ubiquitin‑conjugating enzyme E2 L3; E2 Ubiquitin‑conjugating enzyme L3; Ubiquitin‑conjugating enzyme E2‑F1; Ubiquitin Carrier Protein L3; Ubiquitin‑Protein Ligase L3; L‑UBC; Ubiquitin‑conjugating enzyme E
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P701350
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: UBE2C; Ubiquitin conjugating enzyme E2 C; UBCH10; (E3-Independent) E2 Ubiquitin-conjugating enzyme C; Ubiquitin-conjugating enzyme E2 C; E2 Ubiquitin-conjugating enzyme C; Ubiquitin-Protein Ligase C; Ubiquitin Carrier Protein C; Ubiquitin-conjugating Enzy
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P77272
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2W; Ubiquitin conjugating enzyme E2 W; N‑Terminal E2 Ubiquitin‑conjugating enzyme; E2 Ubiquitin‑conjugating enzyme W; Ubiquitin Carrier Protein W; Ubiquitin‑Protein Ligase W; N‑Terminus‑conjugating E2; UBC‑16; Ubiquitin‑conjugating enzyme E2 W; Ubiquit
Species:
Human
Source:
E. coli
Cat. No.: HY-P71405
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2K; Ubiquitin conjugating enzyme E2 K; HIP2; HYP G; UBC1; Ubiquitin‑conjugating enzyme E2K (UBC1 Homolog, Yeast); Ubiquitin‑conjugating enzyme E2(25K); Ubiquitin‑conjugating enzyme E2 K; E2 Ubiquitin‑conjugating enzyme K; Huntingtin‑Interacting Protein
Species:
Human
Source:
E. coli
Cat. No.: HY-P71404
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2J2; Ubiquitin conjugating enzyme E2 J2; NCUBE2; Non‑Canonical Ubiquitin‑conjugating enzyme 2; Ubiquitin‑conjugating enzyme E2 J2; Ubiquitin‑conjugating enzyme E2, J2 (UBC6 Homolog,Yeast); E2 Ubiquitin‑conjugating enzyme J2; NCUBE‑2; Ubc6p; Ubiquitin‑C
Species:
Human
Source:
E. coli
Cat. No.: HY-P701348
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2L3; Ubiquitin conjugating enzyme E2 L3; UBCH7; Ubiquitin‑conjugating enzyme E2 L3; E2 Ubiquitin‑conjugating enzyme L3; Ubiquitin‑conjugating enzyme E2‑F1; Ubiquitin Carrier Protein L3; Ubiquitin‑Protein Ligase L3; L‑UBC; Ubiquitin‑conjugating enzyme E
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
