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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
VEGF-A-induced FAK phosphorylation
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "VEGF-A-induced FAK phosphorylation" in MCE Product Catalog:
Cat. No.: HY-189430
Target:
Research Areas:
PD-1/PD-L1-IN-69 is an orally active PD-L1 dimerization inducer and FAK phosphorylation inhibitor (IC50 = 18.7 nM for human PD-1/PD-L1 interaction). PD-1/PD-L1-IN-69 blocks the PD-1/PD-L1 interaction by stabilizing dimerization within the PD-L1 dimerization pocket, and inhibits VEGF-A-induced FAK phosphorylation and angiogenesis, thereby enhancing immune-mediated tumor cell death. PD-1/PD-L1-IN-69 can be used for research on colon adenocarcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
