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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
VSIG4
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "VSIG4" in MCE Product Catalog:
Cat. No.: HY-RS15709
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VSIG4 Human Pre-designed siRNA Set A contains three designed siRNAs for VSIG4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17561
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Vsig4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vsig4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24019
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Vsig4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Vsig4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991181
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Cat. No.: HY-P991217
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Cat. No.: HY-P705243
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: V-set and immunoglobulin domain-containing protein 4; VSIG4; Protein Z39Ig; Z39IG; CRIg
Cat. No.: HY-P700898
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CRIg; Z39IG; VSIG4
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Source:
Cat. No.: HY-184555
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TP-18 is a potent and orally active dual EP2/EP4 antagonist with IC50 values of 9.5 nM (EP2) and 3.3 nM (EP4). TP-18 effectively depletes a highly immunosuppressive VSIG4high tumor-associated macrophage (TAM) subset and enhances cytotoxic CD8+ T cell-mediated colorectal cancer (CRC) tumor elimination. TP-18 dampens the expression of VSIG4 by blunting EP2/EP4-Gαs-PKA signaling. TP-18 enhances the sensitivity of anti-PD-1 therapy in CRC mouse models and in patient-derived tumor immune organoids. TP-18 can be used to study colorectal cancer .
Cat. No.: HY-P87145
Synonyms: Complement receptor of the immunoglobulin superfamily antibody; CRIg antibody; Ig superfamily protein antibody; Protein Z39Ig antibody; UNQ317/PRO362 antibody; V set and immunoglobulin domain containing 4 antibody; V-set and immunoglobulin domain-containing protein 4 antibody; VSIG4 antibody; VSIG4_HUMAN antibody; Z39IG antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
