4 Results for "

WM266-4

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "WM266-4" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-14454
CAS No.: 21306-65-0
Purity:  99.81%
Synonyms: Triphenyl Compound A
Research Areas:  

Cancer

TPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a Ki of 0.6 uM. TPh A disrupts the formation of the bcl3–pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells .
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Cat. No.: HY-P991609
CAS No.: 561063-60-3

Target:  

MMP

Research Areas:  

Cancer

ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. ABX-MA1 significantly decreases homotypic aggregation and heterotypic adhesion to HUVECs, and the formation of experimental lung metastasis. ABX-MA1 potently inhibits tumor growth, angiogenesis, and MMP-2 expression in A375SM/WM2664 xenograft mice model, promising for melanoma research .
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Cat. No.: HY-145314
Target:  

Integrin

Research Areas:  

Cancer

TC113 is a c(RGDyK)-Based conjugate of Gemcitabine (GEM). TC113 could be internalized by A549 cells through integrin αvβ3. TC113 shows potent antiproliferative properties against WM266.4 and A549 cells .
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Cat. No.: HY-P992392

Research Areas:  

Cancer

JM1-24-3 is an anti-MUC18 mouse monoclonal antibody with a Kd value of 1.60e-9 M. JM1-24-3 reduces the phosphorylation levels of p-AKT (Ser473) and p-mTOR (Ser2448) in a time-dependent manner. JM1-24-3 exhibits anticancer activity against melanoma. JM1-24-3 can be used in studies related to metastatic melanoma .
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