1 Result for "

WWL0245

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WWL0245" in MCE Product Catalog:

Cat. No.: HY-153519
CAS No.: 2869057-11-2
Research Areas:  

Cancer

WWL0245 is a potent and seletive BRD4 PROTAC. WWL0245 selectively degrades BRD4 with sub-nanomolar DC50 (<1 nM) than BRD2/3 and PLK1 ( DC50>1 μM). WWL0245 shows excellent selective cytotoxicity in the BETi sensitive cancer cell lines, including AR-positive prostate cancer cell lines. WWL0245 is a promising drug candidate for AR-positive prostate cancer research and a valuable tool compound to study the biological function of BRD4 .
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