1 Result for "

XMU-MP-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "XMU-MP-9" in MCE Product Catalog:

Cat. No.: HY-162809
CAS No.: 2251130-41-1
Target:  

Ras

Research Areas:  

Cancer

XMU-MP-9 is a bifunctional compound that binds to the C2 domain of Nedd4-1 and the allosteric site of K-Ras. XMU-MP-9 enhances the interaction between Nedd4-1 and K-Ras, induces conformational changes in the Nedd4-1/K-Ras complex, promotes the ubiquitination and degradation of multiple K-Ras mutants, and inhibits the proliferation of cells carrying K-Ras mutants. XMU-MP-9 can be used for the study of colon, lung and pancreatic cancer .
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