1 Result for "

Y16

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Y16" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-12649
CAS No.: 429653-73-6
Purity:  98.10%
Target:  

Ras

Research Areas:  

Cancer

Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a Kd value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP .
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