1 Result for "

YS370

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YS370" in MCE Product Catalog:

Cat. No.: HY-132866
CAS No.: 2470908-79-1
Purity:  98.07%
Target:  

P-glycoprotein

Research Areas:  

Cancer

YS-370 (compound 44) is a potent, high selective, and orally active inhibitor of P-glycoprotein (P-gp). YS-370 stimulates the P-gp ATPase activity and has moderate inhibition against CYP3A4. YS-370 effectively reverses multidrug resistance (MDR) to paclitaxel and colchicine in SW620/AD300 and HEK293T-ABCB1 cells. YS-370 in combination with paclitaxel achieves much stronger antitumor activity .
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