1 Result for "

ZK53

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ZK53" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-149677
CAS No.: 3031789-26-8
Purity:  98.94%
Research Areas:  

Cancer

ZK53 is a selective activator of mitochondrial caseinolytic protease P (HsClpP) (EC50: 1.37?μM for α-casein hydrolysis by HsClpP). ZK53 is is inactive toward bacterial ClpP proteins. ZK53 induces apoptosis in H1703, H520 and SK-MES-1 cells. ZK53 induces dysregulation of mitochondrial functions in lung squamous cell carcinoma (LUSC) cells. ZK53 inhibits tumor growth in H1703 xenograft mouse model .
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