1 Result for "

ZLDI-8

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ZLDI-8" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-123931
CAS No.: 667880-38-8
Pureté:  98.78%
Domaines de recherche:  

Cancer

ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC50 of 31.6 μM and a Ki of 26.22 μM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32 μM .
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