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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
adenosine-rich conditions
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "adenosine-rich conditions" in MCE Product Catalog:
Cat. No.: HY-189446
CAS No.: 2446776-65-2
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A2A receptor antagonist 4 is an orally active A2A adenosine receptor antagonist with an IC50 of 0.8-1.8 nM and a long receptor residence time. A2A receptor antagonist 4 also exhibits antagonistic activity against A1 and A2B receptors, with IC50 values of 140 nM and 12.3-56.9 nM, respectively. A2A receptor antagonist 4 blocks A2A receptor-mediated adenosine signaling and A2B receptor-mediated adenosine signaling, and remains active under adenosine-rich conditions. A2A receptor antagonist 4 dose-dependently reduces metastatic burden in a lung metastasis model. A2A receptor antagonist 4 can be used for research related to fibrosarcoma and lung metastasis .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
