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anticholinesterase activity

" in MedChemExpress (MCE) Product Catalog:

19

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4

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2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0320C
    Dimethyl sulfoxide
    30+ Cited Publications

    DMSO

    		 Environmental Pollutants Bacterial Cholinesterase (ChE) Inflammation/Immunology
    Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
    Low endotoxin, can be used in various biochemical experiments such as drug dissolution.
    Dimethyl sulfoxide
  • HY-Y0320
    Dimethyl sulfoxide, meets analytical specification of Ch.P.
    340+ Cited Publications

    DMSO, meets analytical specification of Ch.P.

    		 Environmental Pollutants Bacterial Cholinesterase (ChE) Infection Inflammation/Immunology Cancer
    Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
    MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.
    Dimethyl sulfoxide, meets analytical specification of Ch.P.
  • HY-107569
    Garcinol
    5 Publications Verification

    		 Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite Inflammation/Immunology Cancer
    Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
    Garcinol
  • HY-Y0320GL
    Dimethyl sulfoxide (GMP Like)

    DMSO (GMP Like)

    		 Cholinesterase (ChE) Bacterial Infection Inflammation/Immunology Cancer
    Dimethyl sulfoxide (DMSO) (GMP Like) is the GMP Like class Dimethyl sulfoxide (HY-Y0320C). Dimethyl sulfoxide is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
    Dimethyl sulfoxide (GMP Like)
  • HY-B0841
    Acephate
    2 Publications Verification

    		 Environmental Pollutants Cholinesterase (ChE) Neurological Disease
    Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture .
    Acephate
  • HY-Y0320E
    Dimethyl sulfoxide (suitable for HPLC)

    		Cholinesterase (ChE) Bacterial Infection Inflammation/Immunology Cancer
    Dimethyl sulfoxide (suitable for HPLC) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide (suitable for HPLC) is suitable for HPLC .
    Dimethyl sulfoxide (suitable for HPLC)
  • HY-N3894
    Ferulamide

    		nAChR Neurological Disease
    Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities .
    Ferulamide
  • HY-B0841R
    Acephate (Standard)

    		Reference Standards Cholinesterase (ChE) Neurological Disease
    Acephate (Standard) is the analytical standard of Acephate. This product is intended for research and analytical applications. Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture .
    Acephate (Standard)
  • HY-107569R
    Garcinol (Standard)

    		Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite Reference Standards Inflammation/Immunology Cancer
    Garcinol (Standard) is the analytical standard of Garcinol. This product is intended for research and analytical applications. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .
    Garcinol (Standard)
  • HY-122437
    Quinuronium disulfate

    		Bacterial Infection Inflammation/Immunology
    Quinuronium disulfate, a babesicidal agent, possesses anticholinesterase activity .
    Quinuronium disulfate
  • HY-127001
    Lycodine

    		Cholinesterase (ChE) Neurological Disease
    Lycodine is a lycopodium alkaloid, which can be isolated from Huperzia saururus. Lycodine exhibits anticholinesterase activity .
    Lycodine
  • HY-N5089
    (+)-Balanophonin

    		Cholinesterase (ChE) Neurological Disease Metabolic Disease Inflammation/Immunology
    (+)-Balanophonin is a phenolic compound that could be isolated from Passiflora edulis. (+)-Balanophonin possesses anti-oxidant, anticholinesterase, anti-inflammatory, anticancer, and antineurodegenerative activities .
    (+)-Balanophonin
  • HY-175006
    AChE-IN-91

    		Cholinesterase (ChE) Neurological Disease
    AChE-IN-91 (Compound 8u) is a AChE inhibitor with an IC50 of 0.05 μM. AChE-IN-91 has significant anticholinesterase activity, promising for neurological diseases like Alzheimer's disease (AD) research .
    AChE-IN-91
  • HY-W749948
    Acephate-d6

    		Isotope-Labeled Compounds Cholinesterase (ChE) Neurological Disease
    Acephate-d6 is the deuterium labeled Acephate (HY-B0841). Acephate is a broad-spectrum anticholinesterase insecticide. Acephate acts via inhibiting AChE activity of insects. Acephate is used for control of several species of insects in agriculture and in horticulture .
    Acephate-d6
  • HY-W746884
    2-Methyl-2-butenyl (E)-Caffeate

    		Cholinesterase (ChE) Neurological Disease
    2-Methyl-2-butenyl (E)-Caffeate is a type of caffeic acid ester compound. The petroleum ether and chloroform extracts containing 2-Methyl-2-butenyl (E)-Caffeate have inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The ether extract containing 2-Methyl-2-butenyl (E)-Caffeate exhibits strong antioxidant properties. 2-Methyl-2-butenyl (E)-Caffeate can be used in the research of Alzheimer's disease .
    2-Methyl-2-butenyl (E)-Caffeate
  • HY-181597
    LINS05414

    		Cholinesterase (ChE) Histamine Receptor Neurological Disease
    LINS05414 is a histamine H3 receptor ligand with antiCholinesterase and metal chelating activities. LINS05414 exhibits inhibitory activity against acetylcholinesterase (pIC50 = 4.03) and butyrylcholinesterase (pIC50 = 3.83), with a pKi of 6.37 for human histamine H3 receptors. LINS05414 chelates copper ions, ferrous ions and ferric ions. LINS05414 regulates the release of neurotransmitters. LINS05414 can be used in the research of neurodegenerative diseases .
    LINS05414
  • HY-N16847
    3-Methyl-3-butenyl (E)-Caffeate

    		Others Others
    3-Methyl-3-butenyl (E)-Caffeate is a caffeic acid ester compound found in Algerian propolis. Algerian propolis has antioxidant and anticholinesterase activities .
    3-Methyl-3-butenyl (E)-Caffeate
  • HY-179711
    AChE/BChE-IN-32

    		Cholinesterase (ChE) Amyloid-β Neurological Disease
    AChE/BChE-IN-32 (Compound 4a) is an AChE and BChE inhibitor, with Ki values of 2.48 and 0.696 μM respectively. AChE/BChE-IN-32 inhibits Aβ aggregation and exhibits a strong ABTS•+ scavenging ability (TEAC = 2.40). AChE/BChE-IN-32 shows significant neuroprotective activity in glutamate and hydrogen peroxide-induced oxidative stress models. AChE/BChE-IN-32 can be used for the study of Alzheimer's disease .
    AChE/BChE-IN-32
  • HY-W782446
    Dimethyl sulfoxide-13C2

    DMSO-13C2

    		 Isotope-Labeled Compounds Environmental Pollutants Bacterial Cholinesterase (ChE) Inflammation/Immunology
    Dimethyl sulfoxide- 13C2 (DMSO- 13C2) is the 13C-labeled Dimethyl sulfoxide (HY-Y0320C). Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of?other?substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity.
    Dimethyl sulfoxide-13C2

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