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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
apPHOTAC-I-2C
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "apPHOTAC-I-2C" in MCE Product Catalog:
Cat. No.: HY-189451
Target:
Research Areas:
apPHOTAC-I-2C is an arylazopyrazole-based photoswitchable PROTAC and CRBN-binding degrader that binds CRBN with human IC50 values of 15.9 nM and 33.5 nM, and achieves light-controlled targeted degradation of BET proteins (BRD2, BRD3, BRD4) and MTH1 in a manner dependent on CRBN and the proteasome pathway. apPHOTAC-I-2C can be used for research on acute lymphoblastic leukemia .
Cat. No.: HY-189452
Target:
Research Areas:
CRBN ligand-909 is an E3 ligase ligand and can be used in the synthesis of PROTAC apPHOTAC-I-2C (HY-189451) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
