50 Results for "

arthritic

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "arthritic" in MCE Product Catalog:

9
9 Publications Verification
製品番号: HY-N0705
CAS 番号: 85643-19-2
Curculigoside is the main saponin in C. orchioide, exerts significant antioxidant, anti-osteoporosis, antidepressant and neuroprotection effects. Curculigoside possesses significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway .
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3
3 Cited Publications
製品番号: HY-N2513
CAS 番号: 631-69-6
β-Boswellic acid is isolated from the gum resin of Boswellia serrata with anticancer, antioxidant activity, anti-inflammatory activity and anti-arthritic pain.β-Boswellic acid is an orally active nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells with IC50 values ranging from 0.6 to 7.1 μM. β-Boswellic acid is promising for research of diabetes, inflammatory and arthritic diseases .
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3
3 Cited Publications
製品番号: HY-12511
CAS 番号: 72873-74-6
純度:  99.91%
Target:  

p38 MAPK

研究分野:  

Inflammation/Immunology

SKF-86002 is an orally active p38 MAPK inhibitor, with anti-inflammatory, anti-arthritic and analgesic activities. SKF-86002 inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM). SKF-86002 inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid .
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2
2 Cited Publications
製品番号: HY-B1456A
CAS 番号: 29679-58-1
別名: LILLY-53858
研究分野:  

Inflammation/Immunology

Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .
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2
2 Cited Publications
製品番号: HY-N6647
CAS 番号: 20633-84-5
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
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2 Cited Publications
製品番号: HY-111149A
CAS 番号: 1596362-29-6
純度:  95.03%
Target:  

CXCR

研究分野:  

Inflammation/Immunology

PS372424 hydrochloride, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 hydrochloride prevents human T-cell migration in a humanized model of arthritic inflammation .
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2
2 Cited Publications
製品番号: HY-B0288B
CAS 番号: 71720-56-4
別名: LILLY-53858 Calcium hydrate
研究分野:  

Inflammation/Immunology

Fenoprofen (LILLY-53858) Calcium hydrate is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen Calcium hydrate is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen Calcium hydrate also increases ERK1/2 activation in HEK293T cells. Fenoprofen Calcium hydrate has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .
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1
1 Cited Publications
製品番号: HY-108065A
CAS 番号: 128596-80-5
純度:  ≥98.0%
別名: 3'-SL sodium
3'-Sialyllactose (3'-SL) sodium is a prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. 3'-Sialyllactose sodium is an ordinary carbohydrate with the lowest toxicity rating, it can be used for the research of inflammation .
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1 Cited Publications
製品番号: HY-N4136
CAS 番号: 25694-72-8
別名: Veronicastroside
Lonicerin (Veronicastroside) is a flavonoid with multiple biological activities. Lonicerin inhibits xanthine oxidase with an IC50 of 37.4 µg/mL. Lonicerin inhibits alginate secretion protein (AlgE). Lonicerin inhibits P. aeruginosa and C. albicans. Lonicerin has anti-inflammatory, anti-arthritic, antioxidant, antifungal, anti-bacterial, and neuroprotective properties .
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1
1 Cited Publications
製品番号: HY-Y0585
CAS 番号: 611-71-2
D-(-)-Mandelic acid is an orally active alpha hydroxycarboxylic acid that can be isolated from bitter almonds and Indian chestnut trees. It has antioxidant and antibacterial properties and is expected to play an important role in the treatment of rheumatoid arthritis .
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1
1 Cited Publications
製品番号: HY-P0107A
CAS 番号: 1217463-61-0
Target:  

Bombesin Receptor

研究分野:  

Inflammation/Immunology

RC-3095 TFA is a selective bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice .
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1 Cited Publications
製品番号: HY-P0107
CAS 番号: 138147-78-1
Target:  

Bombesin Receptor

研究分野:  

Inflammation/Immunology

RC-3095 is a bombesin/gastrin releasing peptide receptor (GRPR) antagonist . RC-3095 exerts protective effects by reducing gastric oxidative injury in the arthritic mice .
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製品番号: HY-129566
CAS 番号: 56973-41-2
純度:  98.52%
Withanolide B is an active component of W. somnifera Dunal. Withanolide B promotes osteogenic differentiation of hBMSCs via ERK1/2 and Wnt/β-catenin signaling pathways. Withanolide B exhibits neuroprotective, anti-arthritic, anti-aging and anti-cancer effects .
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製品番号: HY-N2923
CAS 番号: 1616-93-9
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase .
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製品番号: HY-108065
CAS 番号: 35890-38-1
別名: 3'-SL
3'-Sialyllactose (3'-SL) is a prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. 3'-Sialyllactose is an ordinary carbohydrate with the lowest toxicity rating, it can be used for the research of inflammation .
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製品番号: HY-N5010
CAS 番号: 569-90-4
別名: Nepetin-7-glucoside
Nepitrin, isolated from Scrophularia striata, possess significant anti-inflammatory and anti-arthritic activity .
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製品番号: HY-136540
CAS 番号: 916888-47-6
別名: RvD3
Target:  

AMPK Autophagy

研究分野:  

Inflammation/Immunology

Resolvin D3 (RvD3) is a docosahexaenoic acid (DHA) derived mediator. Resolvin D3 is dysregulated in arthritis and reduces arthritic inflammation .
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製品番号: HY-111149
CAS 番号: 914291-61-5
Target:  

CXCR

研究分野:  

Inflammation/Immunology

PS372424, a three amino-acid fragment of CXCL10, is a specific human CXCR3 agonist with anti-inflammatory activity. PS372424 prevents human T-cell migration in a humanized model of arthritic inflammation .
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製品番号: HY-B0288A
CAS 番号: 34597-40-5
別名: LILLY-53858 Calcium
研究分野:  

Inflammation/Immunology

Fenoprofen (LILLY-53858) Calcium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen Calcium is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen Calcium also increases ERK1/2 activation in HEK293T cells. Fenoprofen Calcium has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis .
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製品番号: HY-145491
CAS 番号: 578008-43-2
Resolvin D5 is an anti-inflammatory and analgesic agent produced in M2 macrophages. Resolvin D5 alleviates Paclitaxel (HY-B0015)-induced mechanical allodynia and inflammatory pain by activating the GPR32 receptor, with gender specificity (effective only in male mice) and independence from TRPV1 or TRPA1 channels. Resolvin D5 attenuates LPS-induced ERK phosphorylation and NF-κB nuclear translocation, downregulates proinflammatory mediators such as IL-6 and CCL5, inhibits Th17 cell differentiation and osteoclastogenesis, promotes regulatory T cell differentiation, and shows no cytotoxicity to human monocytes. The level of Resolvin D5 is elevated in arthritic SKG mice, but Resolvin D5 has no effect on dendritic cell differentiation or M1 macrophage polarization, nor does it prevent ZyA-induced arthritis progression. Resolvin D5 is suitable for research related to chemotherapy-induced peripheral neuropathy, inflammatory pain and rheumatoid arthritis .
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